circRNA basic information
circBase ID: hsa_circ_0043278
Name: hsa_circ_TADA2A
Synonym: -
Host Gene: hsa-miR-520f
 
 
 
Disease basic information
DO ID:
3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ROCK1, CDKN1B, AKT3
Associated microRNA: hsa-miR-520f
Biological function: promotes non-small cell lung cancer cell proliferation and migration
Molecular mechanism: increasing ROCK1, CDKN1B, and AKT3 expressions through direct inhibition of hsa-miR-520f.
Survival: -
Supported No.:
6
Description:

Circ_0043278 promoted NSCLC cell proliferation, invasion, and migration by increasing ROCK1, CDKN1B, and AKT3 expressions through direct inhibition of miR-520f.

Other information
Title:

A novel circular RNA, hsa_circ_0043278, acts as a potential biomarker and promotes non-small cell lung cancer cell proliferation and migration by regulating miR-520f.

Journal: Artif Cells Nanomed Biotechnol
Published: 2019/3/16
PubMed ID: 30873868