circRNA basic information
circBase ID: hsa_circ_0044073
Name: hsa_circ_GRN
Synonym: CircRNA-0044073
Host Gene: hsa-miR-107
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human umbilical vein endothelial cells (HUVECs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: JAK/STAT
Associated microRNA: hsa-miR-107
Biological function: promoted the proliferation and invasion
Molecular mechanism: favored the activation of the JAK/STAT signaling pathway
Survival: -
Supported No.:
 3
Description:

circRNA_0044073 is upregulated in atherosclerosis and promotes the proliferation and invasion of cells by targeting miR_107 and activating the JAK/STAT signaling pathway, potentially offering a target for novel treatment strategies against atherosclerosis.
Other information
Title:

CircRNA_0044073 is upregulated in atherosclerosis and increases the proliferation and invasion of cells by targeting miR_107.

Journal: Mol Med Rep
Published: 2019/3/14
PubMed ID: 30864721