circRNA basic information
circBase ID: hsa_circ_0055538
Name: hsa_circ_RMND5A
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human OSCC cell lines (SCC9, SCC15, SCC25, CAL27)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: p53, Bcl-2
Associated microRNA: -
Biological function: suppressed in vitro cell proliferation, migration, invasion, and promote apoptosis
Molecular mechanism: hsa_circ_0055538 may affect the development of OSCC via the p53/Bcl-2/caspase signaling pathway
Survival: -
Supported No.:
 1
Description:

Our results indicated that hsa_circ_0055538 is involved in OSCC via the p53 signaling pathway and may be a diagnostic and/or prognostic marker as well as a therapeutic target.
Other information
Title:

Circular RNA hsa_circ_0055538 regulates the malignant biological behavior of oral squamous cell carcinoma through the p53/Bcl-2/caspase signaling pathway.

Journal: J Transl Med
Published: 2019/3/13
PubMed ID: 30857544