circRNA basic information
circBase ID: hsa_circ_0001368
Name: hsa_circ_KLHL24
Synonym: -
Host Gene: hsa-miR-6506-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human GC cell lines (HGC-27, MGC-803, AGS, NUGC-3), GES1and HEK 293T
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXO3
Associated microRNA: hsa-miR-6506-5p
Biological function: suppresses cell proliferation
Molecular mechanism: regulating hsa-miR-6506-5p/FOXO3 axis
Survival: better
Supported No.:
 1
Description:

The hsa_circ_0001368 plays a tumor-suppression role in GC via the miR-6506-5p/FOXO3 axis and may serve as a potential target for GC therapy.
Other information
Title:

Circular RNA hsa_circ_0001368 suppresses the progression of gastric cancer by regulating miR-6506-5p/FOXO3 axis.

Journal: Biochem Biophys Res Commun
Published: 2019/3/12
PubMed ID: 30853185