circRNA basic information
circBase ID: -
Name: hsa_circ_SIRT1
Synonym: circ-Sirt1
Host Gene: hsa-miR-132, hsa-miR-212
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: NF-KB p65
Associated microRNA: hsa-miR-132, hsa-miR-212
Biological function: -
Molecular mechanism: controls NF-kappaB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to hsa-miR-132/212
Survival: -
Supported No.:
 1
Description:

The circ-Sirt1 is a novel non-coding RNA regulator of VSMC phenotype.
Other information
Title:

circ-Sirt1 controls NF-kappaB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle cells.

Journal: Nucleic Acids Res
Published: 2019/3/2
PubMed ID: 30820544