circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-125a, hsa-miR-125b, hsa-let-7b
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MGC-803, AGS cells
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-125a, hsa-miR-125b, hsa-let-7b
Biological function: promoted proliferation
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 6
Description:

CircPVT1 may promote cell proliferation by acting as a sponge for members of the miR-125 family. The level of circPVT1 was observed as an independent prognostic marker for overall survival and disease-free survival of patients with GC.
Other information
Title:

Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer.

Journal: Cancer Lett
Published: 2016/12/18
PubMed ID: 27986464