circRNA basic information
circBase ID: hsa_circ_0000190
Name: hsa_circ_CNIH4
Synonym: -
Host Gene: hsa-miR-767-5p
 
 
 
Disease basic information
DO ID:
 9538
DO name: multiple myeloma
Disease details: multiple myeloma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MM cell lines (MM.1S, NCI-H929)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-767-5p
Biological function: suppressed tumor growth and progression
Molecular mechanism: modulating hsa-miR-767-5p/MAPK4 pathway
Survival: -
Supported No.:
 2
Description:

The ability of circ_0000190 to protect against MM was inherited through repression of miR-767-5p, and miR-767-5p might be a tumor drive through targeting MAPK4.
Other information
Title:

CircRNA circ_0000190 inhibits the progression of multiple myeloma through modulating miR-767-5p/MAPK4 pathway.

Journal: J Exp Clin Cancer Res
Published: 2019/2/8
PubMed ID: 30728056