circRNA basic information
circBase ID: -
Name: hsa_circ_RAD23B
Synonym: -
Host Gene: hsa-miR-593-3p, hsa-miR-653-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: bronchial epithelial cell (16HBE), human NSCLC cell lines (H1299, H1581, H358, A549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCND2 and TIAM1
Associated microRNA: hsa-miR-593-3p, hsa-miR-653-5p
Biological function: Rescue assays proved that circ-RAD23B promotes cell growth via miR-593-3p/CCND2 axis and facilitates cell invasion by miR-653-5p/TIAM1 pathway.
Molecular mechanism: sponge hsa-miR-593-3p and hsa-miR-653-5p and thus elevate CCND2 and TIAM1 expression
Survival: poor
Supported No.:
 3
Description:

circ-RAD23B promotes cell growth and invasion by miR-593-3p/CCND2 and miR-653-5p/TIAM1 pathways in non-small cell lung cancer.
Other information
Title:

Circular RNA circ-RAD23B promotes cell growth and invasion by miR-593-3p/CCND2 and miR-653-5p/TIAM1 pathways in non-small cell lung cancer.

Journal: Biochem Biophys Res Commun
Published: 2019/2/7
PubMed ID: 30722989