circRNA basic information
circBase ID: -
Name: -
Synonym: circNRIP1
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human GC cell lines (BGC-823, SGC-7901, MGC-803, MKN-45, HGC-27, AGS), normal stomach mucosa epithelium cells (GES-1)
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: AKT1
Associated microRNA: hsa-miR-149-5p
Biological function: promote proliferation, migration, invasion
Molecular mechanism: acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway
Survival: -
Supported No.:
 1
Description:

The circNRIP1 sponges miR-149-5p to affect the expression level of AKT1 and eventually acts as a tumour promotor in GC.
Other information
Title:

Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway.

Journal: Mol Cancer
Published: 2019/2/6
PubMed ID: 30717751