circRNA basic information
circBase ID: -
Name: hsa_circ_PRKCI
Synonym: circ-PRKCI
Host Gene: hsa-miR-3680-3p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: ESCC cell lines (TE_1, ECA_109)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT3
Associated microRNA: hsa-miR-3680-3p
Biological function: promote migration and proliferation
Molecular mechanism: as a molecular sponge of hsa-miR-3680-3p, upregulates the expression of AKT
Survival: -
Supported No.:
 2
Description:

The circ-PRKCI/miR-3680-3p/AKT3 regulatory network plays an important role in esophageal squamous cell carcinoma and that provide new insights into the pathogenesis of esophageal squamous cell carcinoma.
Other information
Title:

Circular RNA circ-PRKCI functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-3680-3p in esophageal squamous cell carcinoma.

Journal: J Cell Biochem
Published: 2019/1/20
PubMed ID: 30659640