circRNA basic information
circBase ID: -
Name: hsa_circ_SMAD7
Synonym: circ-SMAD7
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human ESCC cell lines (KYSE30, KYSE 70, KYSE 140, KYSE 150, KYSE 180, TE10, TE12)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: inhibits tumor proliferation and migration
Molecular mechanism: -
Survival: better
Supported No.:
 1
Description:

Our study firstly exposed that over-expressioncirc-SMAD7, an influential regulator in cancer progression, can inhibit tumor proliferation and migration in ESCC and have the potential of becoming a biomarker for the diagnosis and therapy of ESCC.
Other information
Title:

Up-regulation of circ-SMAD7 inhibits tumor proliferation and migration in esophageal squamous cell carcinoma.

Journal: Biomed Pharmacother
Published: 2019/1/6
PubMed ID: 30611100