circRNA basic information
circBase ID: hsa_circ_0099999
Name: hsa_circ_ZMYM2
Synonym: -
Host Gene: hsa-miR-335-5p
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal human pancreatic cell line (HPDE6-C7), PC cell line (CFPAC-1, PANC-1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: JMJD2C
Associated microRNA: hsa-miR-335-5p
Biological function: promoted cell proliferation, invasion while inhibits apoptosis
Molecular mechanism: Competed Endogenously with hsa-miR-335-5p to Regulate JMJD2C
Survival: -
Supported No.:
 2
Description:

Our study demonstrated that circZMYM2 promoted PC progression. CircZMYM2 had a sponge effect on miR-335-5p and modulated the downstream oncogene JMJD2C.
Other information
Title:

circZMYM2 Competed Endogenously with miR-335-5p to Regulate JMJD2C in Pancreatic Cancer.

Journal: Cell Physiol Biochem
Published: 2018/12/12
PubMed ID: 30537731