circRNA basic information
circBase ID: -
Name: hsa_circ_ADAMTS13
Synonym: -
Host Gene: hsa-miR-484
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell line (PLC/PRF/5, SK-Hep-1, Hep3B), hepatoblastoma cell line (HepG2), human Embryonic Kidney 293 (HEK-293), human Embryonic Kidney 293T (HEK-293T)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-484
Biological function: suppresses cell proliferation
Molecular mechanism: sponging hsa-miR-484
Survival: better
Supported No.:
 1
Description:

The circADAMTS13 can serve as a tumor suppressor during HCC progression via the functional pathway of sponging miR-484.
Other information
Title:

Circular RNA profiling identifies circADAMTS13 as a miR-484 sponge which suppresses cell proliferation in hepatocellular carcinoma.

Journal: Mol Oncol
Published: 2018/12/12
PubMed ID: 30537115