circRNA basic information
circBase ID: hsa_circ_0000502
Name: hsa_circ_None
Synonym: circ_0000502
Host Gene: hsa-miR-1238
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: OS cell lines (HOS, Saos2, MG63, U2OS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1238
Biological function: promoted cell proliferation, migration, invasion while inhibits apoptosis
Molecular mechanism: sponging hsa-miR-1238
Survival: poor
Supported No.:
 1
Description:

Circ_0000502 was identified upregulated in both OS tissue specimens and cells. In addition, its expression predicts clinical severity and unfavorable prognosis.For mechanism exploration, circ_0000502 could directly sponge microRNA (miR)-1238.
Other information
Title:

Upregulation of circular RNA circ_0000502 predicts unfavorable prognosis in osteosarcoma and facilitates cell progression via sponging miR-1238.

Journal: J Cell Biochem
Published: 2018/12/14
PubMed ID: 30525215