circRNA basic information
circBase ID: -
Name: -
Synonym: mmu_circ_0001878
Host Gene: mmu-miR-7
 
 
 
Disease basic information
DO ID:
9351
DO name: diabetes mellitus
Disease details: diabetes
Species: mouse
Species details: mouse
Sample type: tissue, cell line
Sample type details: MIN6 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: mmu-miR-7
Biological function: -
Molecular mechanism: inhibit mmu-miR-7; miRNA sponge
Survival: -
Supported No.:
1
Description:

We further identified a new target Myrip in the Cdr1as/miR-7 pathway that regulates insulin granule secretion, and also another target Pax6 that enhances insulin transcription.

Other information
Title:

The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells.

Journal: Sci Rep
Published: 2015/7/28
PubMed ID: 26211738