circRNA basic information
circBase ID: -
Name: -
Synonym: circ_0078767
Host Gene: hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human NSCLC cell lines (A549, HCC827, NCI_H23, H125), normal human lung epithelial cell line (BEAS_2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: RASSF1A
Associated microRNA: hsa-miR-330-3p
Biological function: suppressed NSCLC cell viability, cell cycle progression and invasion while also significantly promoting cell apoptosis.
Molecular mechanism: protecting RASSF1A expression via sponging hsa-miR-330-3p
Survival: -
Supported No.:
 1
Description:

Circ_0078767 could suppress NSCLC progression by inhibiting miR-330-3p, which thereby increased RASSF1 levels.
Other information
Title:

Circ_0078767 suppresses non-small-cell lung cancer by protecting RASSF1A expression via sponging miR-330-3p.

Journal: Cell Prolif
Published: 2018/12/7
PubMed ID: 30507050