circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_100876
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human GC cell lines (MGC_803, HGC_27, BGC_823), normal gastric cell (GES_1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes proliferation, migration, invasion, and epithelial-mesenchymal transition progression
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

CircRNA_100876 expression was upregulated (P<0.05) and was negatively correlated with survival outcome (P<0.05) in ESCC. Inhibition of proliferation, migration, invasion, and epithelial_mesenchymal transition progression was confirmed after circRNA_100876 depletion.
Other information
Title:

Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.

Journal: Onco Targets Ther
Published: 2018/11/15
PubMed ID: 30425526