circRNA basic information
circBase ID: -
Name: -
Synonym: circular RNA-100290
Host Gene: hsa-miR-203
 
 
 
Disease basic information
DO ID:
 9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bone marrow stromal cells (HS-5), AML cells (MV-4- 11, Kasumi-1, HL-60, AML2)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: Rab10
Associated microRNA: hsa-miR-203
Biological function: promotes cell proliferation and inhibits apoptosis
Molecular mechanism: hsa-miR-203/Rab10 axis
Survival: -
Supported No.:
 1
Description:

the present study identifies the crucial regulation of hsa_circ_100290 in AML cell proliferation and apoptosis via targeting the miR-203/Rab10 axis.
Other information
Title:

Circular RNA-100290 promotes cell proliferation and inhibits apoptosis in acute myeloid leukemia cells via sponging miR-203.

Journal: Biochem Biophys Res Commun
Published: 2018/11/15
PubMed ID: 30424877