circRNA basic information
circBase ID: -
Name: mmu_circ_DYM
Synonym: -
Host Gene: mmu-miR-9
 
 
 
Disease basic information
DO ID:
 1470
DO name: major depressive disorder
Disease details: major depressive disorder
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HECTD1, HSP90
Associated microRNA: mmu-miR-9
Biological function: -
Molecular mechanism: targeting mmu-miR-9 to regulate microglial activation via HSP90 ubiquitination
Survival: -
Supported No.:
 1
Description:

the involvement of circDYM and its coupling mechanism in depression, providing translational evidence that circDYM may be a novel therapeutic target for depression.
Other information
Title:

CircDYM ameliorates depressive-like behavior by targeting miR-9 to regulate microglial activation via HSP90 ubiquitination.

Journal: Mol Psychiatry
Published: 2018/11/11
PubMed ID: 30413800