circRNA basic information
circBase ID: -
Name: hsa_circ_UVRAG
Synonym: -
Host Gene: hsa-miR-223
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SV-HUC, BC cell lines (T24, EJ, J82, UM-UC-3, TCC, RT-4)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGFR2
Associated microRNA: hsa-miR-223
Biological function: promote growth and metastasis
Molecular mechanism: suppressed FGFR2 expression by sponging hsa-miR-223
Survival: -
Supported No.:
 2
Description:

Silencing circular RNA UVRAG inhibited bladder cancer growth and metastasis by targeting the miR-223/FGFR2 axis, which may provide a potential biomarker and therapeutic target for the management of BLCA.
Other information
Title:

Silencing circular RNA UVRAG inhibits bladder cancer growth and metastasis by targeting the microRNA-223/fibroblast growth factor receptor 2 axis.

Journal: Cancer Sci
Published: 2018/11/6
PubMed ID: 30387298