circRNA basic information
circBase ID: -
Name: hsa_circ_U2AF1
Synonym: circ-U2AF1
Host Gene: hsa-miR-7-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human glioma cell lines (U87MG, U251)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NOVA2
Associated microRNA: hsa-miR-7-5p
Biological function: promotes human glioma
Molecular mechanism: derepressing neuro-oncological ventral antigen 2 by sponging hsa-miR-7-5p
Survival: poor
Supported No.:
 1
Description:

We suggest that circ-U2AF1 can be a prognostic biomarker and the circ-U2AF1/hsa-miR-7-5p/NOVA2 regulatory pathway may be a novel therapeutic target for treating gliomas.
Other information
Title:

Circ-U2AF1 promotes human glioma via derepressing neuro-oncological ventral antigen 2 by sponging hsa-miR-7-5p.

Journal: J Cell Physiol
Published: 2018/10/21
PubMed ID: 30341906