circRNA basic information
circBase ID: -
Name: hsa_circ_YAP1
Synonym: -
Host Gene: hsa-miR-367-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal human gastric epithelial cell line (GES-1), a GC cell line (HGC-27)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: p27 Kip1
Associated microRNA: hsa-miR-367-5p
Biological function: inhibits the proliferation and invasion
Molecular mechanism: regulating the hsa-miR-367-5p/p27 (Kip1) axis.
Survival: -
Supported No.:
 1
Description:

Our findings demonstrate that circYAP1 functions as a tumor suppressor in GC cells by targeting the miR-367-5p/p27 Kip1 axis and may provide a prognostic indicator of survival in GC patients.
Other information
Title:

Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 (Kip1) axis.

Journal: Mol Cancer
Published: 2018/10/20
PubMed ID: 30336780