circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_001569
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric cancer cell lines (SGC-7901, MGC-803), human normal gastric mucosal cell line (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: NR4A2
Associated microRNA: hsa-miR-145
Biological function: suppresses cell proliferation and invasion and promotes apoptosis
Molecular mechanism: suppressing the expression of hsa-miR-145, which was mediated by NR4A2
Survival: -
Supported No.:
 1
Description:

the present study indicated that overexpressed circRNA_001569 promoted cell viability of gastric cancer through suppressing the expression of miR-145, which was mediated by NR4A2. The research will provide great theoretical basis for further clinical diagnosis and therapy.
Other information
Title:

CircRNA_001569 promotes cell proliferation through absorbing miR-145 in gastric cancer.

Journal: J Biochem
Published: 2018/10/12
PubMed ID: 30304349