circRNA basic information
circBase ID: -
Name: hsa_circ_BCRC-3
Synonym: circular RNA BCRC-3
Host Gene: hsa-miR-182-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human BC cell line (EJ), normal human urothelial cells (SV-HUC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: p27
Associated microRNA: hsa-miR-182-5p
Biological function: suppresses bladder cancer proliferation
Molecular mechanism: directly interact with hsa-miR-182-5p, and subsequently act as a miRNA sponge to promote the hsa-miR-182-5p-targeted 3UTR activity of p27
Survival: -
Supported No.:
 1
Description:

BCRC-3 functions as a tumor inhibitor to suppress BC cell proliferation through miR-182-5p/p27 axis, which would be a novel target for BC therapy.
Other information
Title:

Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis.

Journal: Mol Cancer
Published: 2018/10/5
PubMed ID: 30285878