circRNA basic information
circBase ID: hsa_circ_0061140
Name: hsa_circ_C20orf11
Synonym: -
Host Gene: hsa-miR-370
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: ovarian cancer cell lines (SKOV3, A2780, OV2008, IGROV1, ES-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-370
Biological function: promotes Cell Growth and Metastasis
Molecular mechanism: regulation of the hsa-miR-370/FOXM1 pathway mediating EMT
Survival: -
Supported No.:
 3
Description:

hsa_circ_0061140 appeared to function as a competing endogenous RNA of miR-370 that promoted cell growth and metastasis in ovarian cancer through regulation of the miR-370/FOXM1 pathway mediating EMT.
Other information
Title:

hsa_circ_0061140 Knockdown Reverses FOXM1-Mediated Cell Growth and Metastasis in Ovarian Cancer through miR-370 Sponge Activity.

Journal: Mol Ther Nucleic Acids
Published: 2018/9/22
PubMed ID: 30236833