circRNA basic information
circBase ID: hsa_circ_0020123
Name: hsa_circ_PDZD8
Synonym: -
Host Gene: hsa-miR-144
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: NSCLC cell lines (PC9, H1573, A549, SK-MES-1, H1299, Calu-3)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: EZH2
Associated microRNA: hsa-miR-144
Biological function: promote Proliferation, Migration, and Invasion
Molecular mechanism: hsa_circ_0020123-hsa-miR-144-ZEB1/EZH2 axis
Survival: poor
Supported No.:
 9
Description:

the hsa_circ_0020123-miR-144-ZEB1/EZH2 axis is critical for NSCLC progression, which indicates that hsa_circ_0020123 is a potential target for NSCLC treatment.
Other information
Title:

A novel circular RNA hsa_circ_0020123 exerts oncogenic properties through suppression of miR-144 in non-small cell lung cancer.

Journal: Am J Cancer Res
Published: 2018/9/14
PubMed ID: 30210911