circRNA basic information
circBase ID: -
Name: hsa_circ_NEK6
Synonym: -
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: thyroid cancer cell lines (TPC-1, FTC-133), normal thyroid cell line (Nthy-ori 3_1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: FZD8
Associated microRNA: hsa-miR-370-3p
Biological function: promote the growth and invasion of thyroid cancer cells
Molecular mechanism: up-regulating FZD8 and activating Wnt signaling pathway by targeting hsa-miR-370-3p
Survival: -
Supported No.:
 1
Description:

CircNEK6 promoted the progression of thyroid cancer through up-regulating FZD8 and activating Wnt signaling pathway by targeting miR-370-3p.
Other information
Title:

Emerging roles of circRNA_NEK6 targeting miR-370-3p in the proliferation and invasion of thyroid cancer via Wnt signaling pathway.

Journal: Cancer Biol Ther
Published: 2018/9/13
PubMed ID: 30207869