circRNA basic information
circBase ID: hsa_circ_0080145
Name: hsa_circ_TNS3
Synonym: -
Host Gene: hsa-miR-29b
 
 
 
Disease basic information
DO ID:
 8552
DO name: chronic myeloid leukemia
Disease details: chronic myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CML cell lines (K562, KU812)
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-29b
Biological function: promoted the proliferation
Molecular mechanism: acting as an hsa-miR-29b sponge
Survival: -
Supported No.:
 3
Description:

functional experiments demonstrated that hsa_circ_0080145 knockdown significantly suppressed CML cell proliferation and hsa_circ_0080145 regulated CML cell proliferation by acting as an miR-29b sponge.
Other information
Title:

Global identification of circular RNAs in chronic myeloid leukemia reveals hsa_circ_0080145 regulates cell proliferation by sponging miR-29b.

Journal: Biochem Biophys Res Commun
Published: 2018/9/13
PubMed ID: 30205959