News & Event
Tao Jiang
Introduction of Dr. Tao Jiang, MD & PhD.


Professor of Capital Medical University

Vice director of Beijing Neurosurgical Institute

Director of Glioma Center, Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University

Vice Dean of Department of Clinical Oncology, Capital Medical University

Chairman of Chinese Glioma Genome Atlas project



No.6,TiantanXili, Dongcheng District, Beijing, 100050, P.R. China



1. Wang, Y., T. Qian, G. You, X. Peng, C. Chen, Y. You, K. Yao, C. Wu, J. Ma, Z. Sha, S. Wang, and T. Jiang, Localizing seizure-susceptible brain regions associated with low-grade gliomas using voxel-based lesion-symptom mapping[J]. Neuro Oncol, 2015. 17(2): 282-8.

2. Zhang, T., Y. Wang, X. Fan, J. Ma, S. Li, T. Jiang, and L. Wang, Anatomical localization of p53 mutated tumors: A radiographic study of human glioblastomas[J]. J Neurol Sci, 2014.

3. Zhang, C.B., Z.S. Bao, H.J. Wang, W. Yan, Y.W. Liu, M.Y. Li, W. Zhang, L. Chen, and T. Jiang, Correlation of IDH1/2 mutation with clinicopathologic factors and prognosis in anaplastic gliomas: a report of 203 patients from China[J]. J Cancer Res Clin Oncol, 2014. 140(1): 45-51.

4. Yang, P., G. You, W. Zhang, Y. Wang, K. Yao, and T. Jiang, Correlation of preoperative seizures with clinicopathological factors and prognosis in anaplastic gliomas: A report of 198 patients from China[J]. Seizure, 2014.

5. Yan, W., R. Li, Y. Liu, P. Yang, Z. Wang, C. Zhang, Z. Bao, W. Zhang, Y. You, and T. Jiang, MicroRNA expression patterns in the malignant progression of gliomas and a 5-microRNA signature for prognosis[J]. Oncotarget, 2014. 5(24): 12908-15.

6. Wang, Y.Y., T. Zhang, S.W. Li, T.Y. Qian, X. Fan, X.X. Peng, J. Ma, L. Wang, and T. Jiang, Mapping p53 Mutations in Low-Grade Glioma: A Voxel-Based Neuroimaging Analysis[J]. AJNR Am J Neuroradiol, 2014.

7. Wang, Y., T. Zhang, S. Li, X. Fan, J. Ma, L. Wang, and T. Jiang, Anatomical localization of isocitrate dehydrogenase 1 mutation: a voxel-based radiographic study of 146 low-grade gliomas[J]. Eur J Neurol, 2014.

8. Wang, Y., X. Fan, C. Zhang, T. Zhang, X. Peng, T. Qian, J. Ma, L. Wang, S. Li, and T. Jiang, Identifying radiographic specificity for phosphatase and tensin homolog and epidermal growth factor receptor changes: a quantitative analysis of glioblastomas[J]. Neuroradiology, 2014. 56(12): 1113-20.

9. Wang, Y., X. Fan, C. Zhang, T. Zhang, X. Peng, S. Li, L. Wang, J. Ma, and T. Jiang, Anatomical specificity of O6-methylguanine DNA methyltransferase protein expression in glioblastomas[J]. J Neurooncol, 2014. 120(2): 331-7.

10. Wang, Y., X. Chen, Z. Zhang, S. Li, B. Chen, C. Wu, L. Wang, X. Zhang, J. Wang, L. Chen, and T. Jiang, Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma[J]. Neurosurg Rev, 2014. 37(1): 73-8.

11. Sun, Y., W. Zhang, D. Chen, Y. Lv, J. Zheng, H. Lilljebjorn, L. Ran, Z. Bao, C. Soneson, H.O. Sjogren, L.G. Salford, J. Ji, P.J. French, T. Fioretos, T. Jiang, and X. Fan, A glioma classification scheme based on coexpression modules of EGFR and PDGFRA[J]. Proc Natl Acad Sci U S A, 2014. 111(9): 3538-43.

12. Liu, Y., H. Hu, K. Wang, C. Zhang, Y. Wang, K. Yao, P. Yang, L. Han, C. Kang, W. Zhang, and T. Jiang, Multidimensional analysis of gene expression reveals TGFB1I1-induced EMT contributes to malignant progression of astrocytomas[J]. Oncotarget, 2014.

13. Guo, T., Y. Feng, Q. Liu, X. Yang, T. Jiang, Y. Chen, and Q. Zhang, MicroRNA-320a suppresses in GBM patients and modulates glioma cell functions by targeting IGF-1R[J]. Tumour Biol, 2014.

14. Feng, Y., Z. Wang, Z. Bao, W. Yan, G. You, Y. Wang, H. Hu, W. Zhang, Q. Zhang, and T. Jiang, SOCS3 promoter hypermethylation is a favorable prognosticator and a novel indicator for G-CIMP-positive GBM patients[J]. PLoS One, 2014. 9(3): e91829.

15. Fan, X., Y.Y. Wang, C.B. Zhang, G. You, M.Y. Li, L. Wang, and T. Jiang, Expression of RINT1 predicts seizure occurrence and outcomes in patients with low-grade gliomas[J]. J Cancer Res Clin Oncol, 2014.

16. Cai, J., P. Yang, C. Zhang, W. Zhang, Y. Liu, Z. Bao, X. Liu, W. Du, H. Wang, T. Jiang, and C. Jiang, ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples samples[J]. Oncotarget, 2014. 5(9): 2551-61.

17. Bao, Z.S., G. You, W.B. Li, and T. Jiang, A single aspergillus fumigatus intracranial abscess in an immunocompetent patient with parietal lobe tumorectomy[J]. World J Surg Oncol, 2014. 12(1): 181.

18. Bao, Z.S., M.Y. Li, J.Y. Wang, C.B. Zhang, H.J. Wang, W. Yan, Y.W. Liu, W. Zhang, L. Chen, and T. Jiang, Prognostic value of a nine-gene signature in glioma patients based on mRNA expression profiling[J]. CNS Neurosci Ther, 2014. 20(2): 112-8.

19. Bao, Z.S., H.M. Chen, M.Y. Yang, C.B. Zhang, K. Yu, W.L. Ye, B.Q. Hu, W. Yan, W. Zhang, J. Akers, V. Ramakrishnan, J. Li, B. Carter, Y.W. Liu, H.M. Hu, Z. Wang, M.Y. Li, K. Yao, X.G. Qiu, C.S. Kang, Y.P. You, X.L. Fan, W.S. Song, R.Q. Li, X.D. Su, C.C. Chen, and T. Jiang, RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas[J]. Genome Res, 2014. 24(11): 1765-73.

20. Bao, Z., Y. Feng, H. Wang, C. Zhang, L. Sun, Z. Yan, Q. Liu, T. Guo, M. Li, X. Yang, C. Jiang, Q. Zhang, and T. Jiang, Integrated analysis using methylation and gene expression microarrays reveals PDE4C as a prognostic biomarker in human glioma[J]. Oncol Rep, 2014. 32(1): 250-60.

21. Zhang, W., J. Zhang, W. Yan, G. You, Z. Bao, S. Li, C. Kang, C. Jiang, Y. You, Y. Zhang, C.C. Chen, S.W. Song, and T. Jiang, Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme[J]. Cancer, 2013. 119(4): 814-24.

22. Zhang, W., W. Yan, G. You, Z. Bao, Y. Wang, Y. Liu, Y. You, and T. Jiang, Genome-wide DNA methylation profiling identifies ALDH1A3 promoter methylation as a prognostic predictor in G-CIMP- primary glioblastoma[J]. Cancer Lett, 2013. 328(1): 120-5.

23. Zhang, J.X., J. Zhang, W. Yan, Y.Y. Wang, L. Han, X. Yue, N. Liu, Y.P. You, T. Jiang, P.Y. Pu, and C.S. Kang, Unique genome-wide map of TCF4 and STAT3 targets using ChIP-seq reveals their association with new molecular subtypes of glioblastoma[J]. Neuro Oncol, 2013. 15(3): 279-89.

24. Zhang, J.X., L. Han, Z.S. Bao, Y.Y. Wang, L.Y. Chen, W. Yan, S.Z. Yu, P.Y. Pu, N. Liu, Y.P. You, T. Jiang, and C.S. Kang, HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma[J]. Neuro Oncol, 2013. 15(12): 1595-603.

25. You, G., L. Feng, W. Yan, W. Zhang, Y.Z. Wang, S.W. Li, S.W. Li, G.L. Li, Y.J. Song, C.S. Kang, Y.P. You, and T. Jiang, BCL2A1 is a potential biomarker for postoperative seizure control in patients with low-grade gliomas[J]. CNS Neurosci Ther, 2013. 19(11): 882-8.

26. Yang, P., Y. Wang, X. Peng, G. You, W. Zhang, W. Yan, Z. Bao, Y. Wang, X. Qiu, and T. Jiang, Management and survival rates in patients with glioma in China (2004-2010): a retrospective study from a single-institution[J]. J Neurooncol, 2013. 113(2): 259-66.

27. Yan, Z.H., Z.S. Bao, W. Yan, Y.W. Liu, C.B. Zhang, H.J. Wang, Y. Feng, Y.Z. Wang, W. Zhang, G. You, Q.G. Zhang, and T. Jiang, Upregulation of DLX2 confers a poor prognosis in glioblastoma patients by inducing a proliferative phenotype[J]. Curr Mol Med, 2013. 13(3): 438-45.

28. Wang, Y. and T. Jiang, Understanding high grade glioma: molecular mechanism, therapy and comprehensive management[J]. Cancer Lett, 2013. 331(2): 139-46.

29. Wang, X., Y.Y. Wang, T. Jiang, Y.Z. Wang, and C.X. Wu, Direct evidence of the left caudate's role in bilingual control: an intra-operative electrical stimulation study[J]. Neurocase, 2013. 19(5): 462-9.

30. Wang, L.J., Y. Bai, Z.S. Bao, Y. Chen, Z.H. Yan, W. Zhang, and Q.G. Zhang, Hypermethylation of testis derived transcript gene promoter significantly correlates with worse outcomes in glioblastoma patients[J]. Chin Med J (Engl), 2013. 126(11): 2062-6.

31. Liu, Y., K. Tang, W. Yan, Y. Wang, G. You, C. Kang, T. Jiang, and W. Zhang, Identifying Ki-67 specific miRNA-mRNA interactions in malignant astrocytomas[J]. Neurosci Lett, 2013. 546: 36-41.

32. Li, W.B., H.Y. Chen, W. Zhang, W. Yan, R. Shi, S.W. Li, and T. Jiang, Relationship between magnetic resonance imaging features and miRNA gene expression in patients with glioblastoma multiforme[J]. Chin Med J (Engl), 2013. 126(15): 2881-5.

33. Chen, Y.D., X. Zhang, X.G. Qiu, J. Li, Q. Yuan, T. Jiang, and M. Yang, Functional FEN1 genetic variants and haplotypes are associated with glioma risk[J]. J Neurooncol, 2013. 111(2): 145-51.

34. Bao, Z., C. Zhang, W. Yan, Y. Liu, M. Li, W. Zhang, and T. Jiang, BMP4, a strong better prognosis predictor, has a subtype preference and cell development association in gliomas[J]. J Transl Med, 2013. 11: 100.

35. Zhao, P., L. Zhao, P. Zou, A. Lu, N. Liu, W. Yan, C. Kang, Z. Fu, Y. You, and T. Jiang, Genetic oxidative stress variants and glioma risk in a Chinese population: a hospital-based case-control study[J]. BMC Cancer, 2012. 12: 617.

36. Zhang, W., J. Zhang, K. Hoadley, D. Kushwaha, V. Ramakrishnan, S. Li, C. Kang, Y. You, C. Jiang, S.W. Song, T. Jiang, and C.C. Chen, miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression[J]. Neuro Oncol, 2012. 14(6): 712-9.

37. You, G., W. Yan, W. Zhang, Y. Wang, Z. Bao, S. Li, S. Li, G. Li, Y. Song, C. Kang, and T. Jiang, Significance of miR-196b in tumor-related epilepsy of patients with gliomas[J]. PLoS One, 2012. 7(9): e46218.

38. You, G., Z.Y. Sha, W. Yan, W. Zhang, Y.Z. Wang, S.W. Li, L. Sang, Z. Wang, G.L. Li, S.W. Li, Y.J. Song, C.S. Kang, and T. Jiang, Seizure characteristics and outcomes in 508 Chinese adult patients undergoing primary resection of low-grade gliomas: a clinicopathological study[J]. Neuro Oncol, 2012. 14(2): 230-41.

39. You, G., Z. Sha, and T. Jiang, The pathogenesis of tumor-related epilepsy and its implications for clinical treatment[J]. Seizure, 2012. 21(3): 153-9.

40. You, G., L. Huang, P. Yang, W. Zhang, W. Yan, Y. Wang, Z. Bao, S. Li, S. Li, G. Li, and T. Jiang, Clinical and molecular genetic factors affecting postoperative seizure control of 183 Chinese adult patients with low-grade gliomas[J]. Eur J Neurol, 2012. 19(2): 298-306.

41. Yan, W., W. Zhang, G. You, J. Zhang, L. Han, Z. Bao, Y. Wang, Y. Liu, C. Jiang, C. Kang, Y. You, and T. Jiang, Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group[J]. Neuro Oncol, 2012. 14(12): 1432-40.

42. Yan, W., W. Zhang, G. You, Z. Bao, Y. Wang, Y. Liu, C. Kang, Y. You, L. Wang, and T. Jiang, Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China[J]. PLoS One, 2012. 7(1): e30339.

43. Wang, Y., S. Li, L. Chen, G. You, Z. Bao, W. Yan, Z. Shi, Y. Chen, K. Yao, W. Zhang, C. Kang, and T. Jiang, Glioblastoma with an oligodendroglioma component: distinct clinical behavior, genetic alterations, and outcome[J]. Neuro Oncol, 2012. 14(4): 518-25.

44. Wang, X.F., Z.M. Shi, X.R. Wang, L. Cao, Y.Y. Wang, J.X. Zhang, Y. Yin, H. Luo, C.S. Kang, N. Liu, T. Jiang, and Y.P. You, MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2[J]. J Cancer Res Clin Oncol, 2012. 138(4): 573-84.

45. Tang, K., Q. Jin, W. Yan, W. Zhang, G. You, Y. Liu, and T. Jiang, Clinical correlation of MGMT protein expression and promoter methylation in Chinese glioblastoma patients[J]. Med Oncol, 2012. 29(2): 1292-6.

46. Ma, R., W. Yan, G. Zhang, H. Lv, Z. Liu, F. Fang, W. Zhang, J. Zhang, T. Tao, Y. You, T. Jiang, and X. Kang, Upregulation of miR-196b confers a poor prognosis in glioblastoma patients via inducing a proliferative phenotype[J]. PLoS One, 2012. 7(6): e38096.

47. Ma, R., T. Jiang, and X. Kang, Circulating microRNAs in cancer: origin, function and application[J]. J Exp Clin Cancer Res, 2012. 31: 38.

48. Liu, Y., W. Yan, W. Zhang, L. Chen, G. You, Z. Bao, Y. Wang, H. Wang, C. Kang, and T. Jiang, MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1[J]. Oncol Rep, 2012. 28(3): 1013-21.

49. Li, Y., T. Jiang, J. Zhang, B. Zhang, W. Yang, G. You, K. Xu, J. Wu, C. Luo, and S.W. Song, Elevated serum antibodies against insulin-like growth factor-binding protein-2 allow detecting early-stage cancers: evidences from glioma and colorectal carcinoma studies[J]. Ann Oncol, 2012. 23(9): 2415-22.

50. Li, S., C. Yan, L. Huang, X. Qiu, Z. Wang, and T. Jiang, Molecular prognostic factors of anaplastic oligodendroglial tumors and its relationship: a single institutional review of 77 patients from China[J]. Neuro Oncol, 2012. 14(1): 109-16.

51. Han, L., X. Yue, X. Zhou, F.M. Lan, G. You, W. Zhang, K.L. Zhang, C.Z. Zhang, J.Q. Cheng, S.Z. Yu, P.Y. Pu, T. Jiang, and C.S. Kang, MicroRNA-21 expression is regulated by beta-catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK[J]. CNS Neurosci Ther, 2012. 18(7): 573-83.

52. Chen, Q., X.Z. Chen, J.M. Wang, S.W. Li, T. Jiang, and J.P. Dai, Intracranial meningeal hemangiopericytomas in children and adolescents: CT and MR imaging findings[J]. AJNR Am J Neuroradiol, 2012. 33(1): 195-9.

53. Chen, L., W. Zhang, W. Yan, L. Han, K. Zhang, Z. Shi, J. Zhang, Y. Wang, Y. Li, S. Yu, P. Pu, C. Jiang, T. Jiang, and C. Kang, The putative tumor suppressor miR-524-5p directly targets Jagged-1 and Hes-1 in glioma[J]. Carcinogenesis, 2012. 33(11): 2276-82.

54. You, G., W. Yan, W. Zhang, S. Li, G. Li, and T. Jiang, Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature[J]. World J Surg Oncol, 2011. 9: 97.

55. Yan, W., W. Zhang, L. Sun, Y. Liu, G. You, Y. Wang, C. Kang, Y. You, and T. Jiang, Identification of MMP-9 specific microRNA expression profile as potential targets of anti-invasion therapy in glioblastoma multiforme[J]. Brain Res, 2011. 1411: 108-15.

56. Yan, W., W. Zhang, and T. Jiang, Oncogene addiction in gliomas: implications for molecular targeted therapy[J]. J Exp Clin Cancer Res, 2011. 30: 58.

57. Wang, Y., L. Chen, Z. Bao, S. Li, G. You, W. Yan, Z. Shi, Y. Liu, P. Yang, W. Zhang, L. Han, C. Kang, and T. Jiang, Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways[J]. Oncol Rep, 2011. 26(5): 1173-80.

58. Pu, S., Y.N. Li, C.X. Wu, Y.Z. Wang, X.L. Zhou, and T. Jiang, Cortical areas involved in numerical processing: an intraoperative electrostimulation study[J]. Stereotact Funct Neurosurg, 2011. 89(1): 42-7.

59. Jin, Q., W. Zhang, X.G. Qiu, W. Yan, G. You, Y.W. Liu, T. Jiang, and L. Wang, Gene expression profiling reveals Ki-67 associated proliferation signature in human glioblastoma[J]. Chin Med J (Engl), 2011. 124(17): 2584-8.

60. Jiang, T., G.F. Tang, Y. Lin, X.X. Peng, X. Zhang, X.W. Zhai, X. Peng, J.Q. Yang, H.E. Huang, N.F. Wu, X.J. Chen, H.X. Xing, T.Y. Su, and Z.C. Wang, Prevalence estimates for primary brain tumors in China: a multi-center cross-sectional study[J]. Chin Med J (Engl), 2011. 124(17): 2578-83.

61. Huang, L., G. You, T. Jiang, G. Li, S. Li, and Z. Wang, Correlation between tumor-related seizures and molecular genetic profile in 103 Chinese patients with low-grade gliomas: a preliminary study[J]. J Neurol Sci, 2011. 302(1-2): 63-7.

62. Zhang, W., Y. Lin, B. Chen, S.W. Song, and T. Jiang, Recurrent glioblastoma of childhood treated with bevacizumab: case report and molecular features[J]. Childs Nerv Syst, 2010. 26(1): 137-43.

63. Han, L., Y. Yang, X. Yue, K. Huang, X. Liu, P. Pu, H. Jiang, W. Yan, T. Jiang, and C. Kang, Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of beta-catenin-mediated transcription[J]. Brain Res, 2010. 1366: 9-17.

64. Chen, X., J. Dai, and T. Jiang, Supratentorial WHO grade II glioma invasion: a morphologic study using sequential conventional MRI[J]. Br J Neurosurg, 2010. 24(2): 196-201.

65. Lin, Y., T. Jiang, K. Zhou, L. Xu, B. Chen, G. Li, X. Qiu, T. Jiang, W. Zhang, and S.W. Song, Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas[J]. Neuro Oncol, 2009. 11(5): 468-76.

66. Li, S.W., X.G. Qiu, B.S. Chen, W. Zhang, H. Ren, Z.C. Wang, and T. Jiang, Prognostic factors influencing clinical outcomes of glioblastoma multiforme[J]. Chin Med J (Engl), 2009. 122(11): 1245-9.

67. Li, S.W. and T. Jiang, Advances in the adjuvant chemotherapy of glioblastoma multiforme: opportunities and challenges for the neurosurgeons in China[J]. Chin Med J (Engl), 2009. 122(11): 1243-4.

68. Huang, L., T. Jiang, F. Yuan, G.L. Li, Y. Cui, E.Z. Liu, and Z.C. Wang, Correlation of chromosomes 1p and 19q status and expressions of O6-methylguanine DNA methyltransferase (MGMT), p53 and Ki-67 in diffuse gliomas of World Health Organization (WHO) grades II and III: a clinicopathological study[J]. Neuropathol Appl Neurobiol, 2009. 35(4): 367-79.

69. Zhang, Z., T. Jiang, J. Xie, F.S. Liu, S.W. Li, H. Qiao, and Z.C. Wang, Surgical strategies for glioma involving language areas[J]. Chin Med J (Engl), 2008. 121(18): 1800-5.

70. Xie, J., X.Z. Chen, T. Jiang, S.W. Li, Z.X. Li, Z. Zhang, J.P. Dai, and Z.C. Wang, Preoperative blood oxygen level-dependent functional magnetic resonance imaging in patients with gliomas involving the motor cortical areas[J]. Chin Med J (Engl), 2008. 121(7): 631-5.

71. Li, S., T. Jiang, G. Li, and Z. Wang, Impact of p53 status to response of temozolomide in low MGMT expression glioblastomas: preliminary results[J]. Neurol Res, 2008. 30(6): 567-70.

72. Huang, L., T. Jiang, F. Yuan, G.L. Li, E.Z. Liu, and Z.C. Wang, Correlations between molecular profile and tumor location in Chinese patients with oligodendroglial tumors[J]. Clin Neurol Neurosurg, 2008. 110(10): 1020-4.

73. Chen, X.Z., T. Jiang, S.W. Li, L. Ai, and J.P. Dai, Dynamic radiological change of gliomas located in the paralimbic system and its clinical significance[J]. Chin Med J (Engl), 2008. 121(8): 713-5.

74. Tian, L., T. Jiang, M. Liang, X. Li, Y. He, K. Wang, B. Cao, and T. Jiang, Stabilities of negative correlations between blood oxygen level-dependent signals associated with sensory and motor cortices[J]. Hum Brain Mapp, 2007. 28(7): 681-90.