circRNA basic information
circBase ID: hsa_circ_0007534
Name: hsa_circ_DDX42
Synonym: -
Host Gene: hsa-miR-593
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BC cell lines (MCF-1, MDA-MB-231, MDA-MB-468, SKBR-3, MDA-MB-453), normal human mammary epithelial cell line (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MUC19
Associated microRNA: hsa-miR-593
Biological function: promote cell proliferation and invasion
Molecular mechanism: acting as a hsa-miR-593 sponge to promote MUC19 expression
Survival: -
Supported No.:
 1
Description:

Our findings suggest an oncogenic role for hsa_circ_0007534 in BC by acting as a miR-593 sponge to promote MUC19 expression.
Other information
Title:

Downregulation of hsa_circ_0007534 suppresses breast cancer cell proliferation and invasion by targeting miR-593/MUC19 signal pathway.

Journal: Biochem Biophys Res Commun
Published: 2018/8/25
PubMed ID: 30139516