circRNA basic information
circBase ID: -
Name: hsa_circ_CEP128
Synonym: -
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bladder cancer cells lines (RT-112, 5637, BIU-87, TCCSUP), human embryonic kidney cells lines (HEK293T)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX11
Associated microRNA: hsa-miR-145-5p
Biological function: promote cell proliferation and inhibit cell apoptosis
Molecular mechanism: functions as a ceRNA for hsa-miR-145-5p, which could up regulates SOX11
Survival: -
Supported No.:
 2
Description:

CircCEP128 functions as a ceRNA for miR-145-5p, which could up regulates SOX11 and further promotes cell proliferation and inhibits cell apoptosis of bladder cancer.
Other information
Title:

Circular RNA CEP128 acts as a sponge of miR-145-5p in promoting the bladder cancer progression via regulating SOX11.

Journal: Mol Med
Published: 2018/8/24
PubMed ID: 30134837