circRNA basic information
circBase ID: hsa_circ_0015758
Name: hsa_circ_CFH
Synonym: circular RNA Complement Factor H (CFH)
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: normal human astrocytes (NHAs), human glioblastoma cell lines (U87, A172, U251, TJ905, U373)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT1
Associated microRNA: hsa-miR-149
Biological function: promote cell proliferation and colony formation abilities
Molecular mechanism: Sponging hsa-miR-149 and Regulating AKT1
Survival: -
Supported No.:
 1
Description:

Circ-CFH promotes glioma progression by sponging miR-149 and regulating the AKT1 signaling pathway. The circ-CFH/miR-149/AKT1 regulation axis may be a potential target for glioma therapy.
Other information
Title:

Circular RNA Complement Factor H (CFH) Promotes Glioma Progression by Sponging miR-149 and Regulating AKT1.

Journal: Med Sci Monit
Published: 2018/8/17
PubMed ID: 30111766