circRNA basic information
circBase ID: hsa_circ_0016760
Name: hsa_circ_SNAP47
Synonym: circ_0016760
Host Gene: hsa-miR-1287
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NSCLC cell lines (A549, H358, H1299, H1975), normal bronchial epithelial cell line (16HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GAGE1
Associated microRNA: hsa-miR-1287
Biological function: promote cell growth and metastatic properties and inhibit cell apoptosis
Molecular mechanism: circ_0016760/hsa-miR-1287/GAGE1 signaling
Survival: poor
Supported No.:
 6
Description:

Circ_0016760/miR-1287/GAGE1 signaling might play vital roles in the tumorigenesis and progression of NSCLC.
Other information
Title:

Upregulated circular RNA circ_0016760 indicates unfavorable prognosis in NSCLC and promotes cell progression through miR-1287/GAGE1 axis.

Journal: Biochem Biophys Res Commun
Published: 2018/8/15
PubMed ID: 30103946