circRNA basic information
circBase ID: -
Name: -
Synonym: circ_001569
Host Gene: hsa-miR-411-5p, hsa-miR-432-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal liver cell (L02), liver cancer cell line (HepG2), HCC cells (Huh7, SMMC7721, Sk-Hep-1, HCCLM3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-411-5p, hsa-miR-432-5p
Biological function: promotes cell growth and metastasis
Molecular mechanism: sponging hsa-miR-411-5p and hsa-miR-432-5p
Survival: poor
Supported No.:
 1
Description:

In summary, circ_001569/miR-411-5p/miR-432-5p regulatory signaling might be a rational HCC-related therapeutic target.
Other information
Title:

Overexpression of circular RNA circ_001569 indicates poor prognosis in hepatocellular carcinoma and promotes cell growth and metastasis by sponging miR-411-5p and miR-432-5p.

Journal: Biochem Biophys Res Commun
Published: 2018/8/9
PubMed ID: 30086881