circRNA basic information
circBase ID: -
Name: hsa_circ_FBLIM1
Synonym: -
Host Gene: hsa-miR-346
 
 
 
Disease basic information
DO ID:
 687
DO name: hepatoblastoma
Disease details: hepatoblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal liver cell line (LO2), HCC cell lines (HepG2, 7402, 97H)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-346
Biological function: promote hepatocellular cancer progression
Molecular mechanism: sponging hsa-miR-346
Survival: -
Supported No.:
 1
Description:

Taken together, we conclude that circFBLIM1 may function as a competing endogenous RNA (ceRNA) to regulate FBLIM1 expression through sponging miR-346 to exert regulatory functions in HCC. circFBLIM1 may be a diagnostic biomarker and potential target for HCC therapy.
Other information
Title:

circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346.

Journal: J Exp Clin Cancer Res
Published: 2018/7/29
PubMed ID: 30053867