circRNA basic information
circBase ID: -
Name: -
Synonym: circ_0001649
Host Gene: hsa-miR-331-3p, hsa-miR-338-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human NSCLC cell lines (A549, H358, H1299, H1581)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-331-3p, hsa-miR-338-5p
Biological function: inhibits cell proliferation, migration and invasion
Molecular mechanism: sponging hsa-miR-331-3p and hsa-miR-338-5p
Survival: better
Supported No.:
 1
Description:

Collectively, this study suggested that circ_0001649/miR-331-3p/miR-338-5p regulatory signaling might be a potential target for NSCLC therapy.
Other information
Title:

Circular RNA circ_0001649 acts as a prognostic biomarker and inhibits NSCLC progression via sponging miR-331-3p and miR-338-5p.

Journal: Biochem Biophys Res Commun
Published: 2018/7/22
PubMed ID: 30029881