circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-7
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: lung cancer cell lines (A549, H460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EGFR, CCNE1, PIK3CD
Associated microRNA: hsa-miR-7
Biological function: promote the tumor progression
Molecular mechanism: functioned as hsa-miR-7 sponges to up-regulate the key target genes of hsa-miR-7 including EGFR, CCNE1 and PIK3CD
Survival: poor
Supported No.:
 5
Description:

Overexpressed CDR1as in NSCLC functions promotes the tumor progression via miR-7 signals.
Other information
Title:

Overexpressed CDR1as functions as an oncogene to promote the tumor progression via miR-7 in non-small-cell lung cancer.

Journal: Onco Targets Ther
Published: 2018/7/20
PubMed ID: 30022841