circRNA basic information
circBase ID: hsa_circ_0001649
Name: hsa_circ_SHPRH
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: glioma cells (U251, U118, LN229, U87MG), normal human astrocytes (NHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: Bcl-2, caspase-3
Associated microRNA: -
Biological function: inhibits glioma cell growth
Molecular mechanism: regulating Bcl-2/caspase-3 pathway
Survival: better
Supported No.:
 2
Description:

Ultimately, this study suggests that hsa_circ_0001649 may be a potential glioma-related prognostic/therapeutic target.
Other information
Title:

Decreased circular RNA hsa_circ_0001649 predicts unfavorable prognosis in glioma and exerts oncogenic properties in vitro and in vivo.

Journal: Gene
Published: 2018/7/18
PubMed ID: 30016668