circRNA basic information
circBase ID:
-
Name:
hsa_circ_Dnmt1
Synonym:
circ-Dnmt1
Host Gene:
-
Disease basic information
DO ID:
1612
DO name:
breast cancer
Disease details:
breast cancer
Species:
human
Species details:
human
Sample type:
cell line
Sample type details:
human non-cancer cell lines (HaCaT, 293T, BEAS2B, Jurkat, HUVEC, MCF10A), breast cancer cell lines (MCF-7, MDA-MB468, MDA-MB-231, HTB126, SK-BR-3), other tumor cell lines (H460, LnCap, Du145, PC3, JHH1, SNU449, HepG2, Hela)
circRNA-disease information
Detected method:
M
Detected method confidence
Low
Expression pattern:
UP
Associated gene:
p53
,
AUF1
Associated microRNA:
-
Biological function:
activating autophagy
Molecular mechanism:
circ-Dnmt1 could interact with both p53 and AUF1, promoting the nuclear translocation of both proteins
Survival:
-
Supported No.:
1
Description:
A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy.
Other information
Title:
A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy.
Journal:
Oncogene
Published:
2018/7/6
PubMed ID:
29973691