circRNA basic information
circBase ID: hsa_circ_0000518
Name: hsa_circ_RPPH1
Synonym: circRNA_000167
Host Gene: hsa-miR-181a-2*, hsa-miR-521, hsa-miR-556-5p, hsa-miR-512-5p, hsa-miR-663b, hsa-miR-1204
 
 
 
Disease basic information
DO ID:
 1107
DO name: esophageal carcinoma
Disease details: radioresistant esophageal cancer cells
Species: human
Species details: human
Sample type: cell line
Sample type details: human esophageal squamous cancer cell lines (KYSE-150)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-181a-2*, hsa-miR-521, hsa-miR-556-5p, hsa-miR-512-5p, hsa-miR-663b, hsa-miR-1204
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

To validate the microarray profiling expression data, realtime quantitative RT-PCR revealed 4 upregulated and 5 downregulated expressed circRNAs as shown in Fig. 2. Expression levels detected by the two methods were consistent with each other, demonstrating the high reliability of the microarray expression results. Our study revealed a comprehensive expression and functional profile of differentially expressed circRNAs in radioresistant esophageal cancer cells, indicating possible involvement of these dysregulated circRNAs in the development of radiation resistance.
Other information
Title:

Profiling and bioinformatics analyses reveal differential circular RNA expression in radioresistant esophageal cancer cells.

Journal: J Transl Med
Published: 2016/7/29
PubMed ID: 27465405