circRNA basic information
circBase ID: hsa_circ_0026344
Name: hsa_circ_ACVRL1
Synonym: circ_0026344
Host Gene: hsa-miR-21, hsa-miR-31
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human CRC cell lines (HCT116, SW480, SW620, HT29), normal colon cell lines (NCM460, FHC), 293 T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-21, hsa-miR-31
Biological function: decreased the growth and invasion while promoting apoptosis
Molecular mechanism: sponging hsa-miR-21 and hsa-miR-31
Survival: better
Supported No.:
 2
Description:

In conclusion, this study revealed that circ_0026344/miR-21/miR-31 regulatory signaling was implicated in CRC progression.
Other information
Title:

CircRNA circ_0026344 as a prognostic biomarker suppresses colorectal cancer progression via microRNA-21 and microRNA-31.

Journal: Biochem Biophys Res Commun
Published: 2018/6/22
PubMed ID: 29928882