Description: |
To validate the microarray profiling expression data, realtime quantitative RT-PCR revealed 4 upregulated and 5 downregulated expressed circRNAs as shown in Fig. 2. Expression levels detected by the two methods were consistent with each other, demonstrating the high reliability of the microarray expression results. Our study revealed a comprehensive expression and functional profile of differentially expressed circRNAs in radioresistant esophageal cancer cells, indicating possible involvement of these dysregulated circRNAs in the development of radiation resistance. |