circRNA basic information
circBase ID: hsa_circ_0067934
Name: hsa_circ_PRKCI
Synonym: circ_0067934
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H1299, H358, SPCA1), a normal cell line (MRC-5)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promoting proliferation, migration and invasion
Molecular mechanism: modulate the expression levels of markers of epithelial-to-mesenchymal transition
Survival: poor
Supported No.:
 3
Description:

Our data suggested that circ_0067934 functioned as an oncogenic circular RNA in NSCLC, which provided a potential prognostic biomarker and therapeutic target for NSCLC.
Other information
Title:

CircRNA circ_0067934 silencing inhibits the proliferation, migration and invasion of NSCLC cells and correlates with unfavorable prognosis in NSCLC.

Journal: Eur Rev Med Pharmacol Sci
Published: 2018/6/5
PubMed ID: 29863250