circRNA basic information
circBase ID: hsa_circ_0008717
Name: hsa_circ_ABCB10
Synonym: circRNA-0008717
Host Gene: hsa-miR-203
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human osteosarcoma cell lines MG-63, SAOS-2, U-2OS, HOS, SW1353, one osteoblastic cell line (hFOB1.19)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: Bmi-1
Associated microRNA: hsa-miR-203
Biological function: promotion of osteosarcoma cell proliferation and invasion
Molecular mechanism: elevate Bmi-1 expression
Survival: poor
Supported No.:
 1
Description:

CircRNA-0008717 plays an oncogenic role in osteosarcoma and may serve as a promising prognostic biomarker for osteosarcoma patients. Therefore, silence of circRNA-0008717 could be a future direction to develop a novel treatment strategy.
Other information
Title:

Identification and functional characterization of circRNA-0008717 as an oncogene in osteosarcoma through sponging miR-203.

Journal: Oncotarget
Published: 2018/6/2
PubMed ID: 29854278