circRNA basic information
circBase ID: -
Name: hsa_circ_Cul2
Synonym: circ-10720
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: PLC-PRF-5, SMMC-7721, HEK-293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Twist1
Associated microRNA: -
Biological function: -
Molecular mechanism: Promote EMT
Survival: poor
Supported No.:
 1
Description:

A circRNA-based mechanism drives Twist1-mediated regulation of vimentin during EMT and provides potential therapeutic targets for treatment of HCC.
Other information
Title:

Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma.

Journal: Cancer Res
Published: 2018/5/31
PubMed ID: 29844124