circRNA basic information
circBase ID: hsa_circ_0008039
Name: hsa_circ_PRKAR1B
Synonym: -
Host Gene: hsa-miR-432-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: breast cancer cell lines (BT-20, BT-474, MCF-7, BT549, MDA-MB231, SKBR-3), normal human breast epithelial cells (MCF10 A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F3
Associated microRNA: hsa-miR-432-5p
Biological function: promotes breast cancer cell proliferation and migration
Molecular mechanism: hsa_circ_0008039/hsa-miR-432-5p/E2F3 axis
Survival: -
Supported No.:
 2
Description:

our study indicated that hsa_circ_0008039 exerted oncogenic roles in breast cancer and suggested the hsa_circ_0008039/miR-432-5p/E2F3 axis might be a potential therapeutic target.
Other information
Title:

Circular RNA hsa_circ_0008039 promotes breast cancer cell proliferation and migration by regulating miR-432-5p/E2F3 axis.

Journal: Biochem Biophys Res Commun
Published: 2018/5/29
PubMed ID: 29807010