circRNA basic information
circBase ID: hsa_circ_0141940
Name: hsa_circ_MYLK
Synonym: circRNA-MYLK
Host Gene: hsa-miR-29a
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PCa cell lines (DU145, LNCaP, PC-3, PC-3MIE8), normal prostatic cell line (WPMY-1 cell)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-29a
Biological function: promoted PCa cells proliferation, invasion, and migration
Molecular mechanism: targeting hsa-miR-29a
Survival: -
Supported No.:
 1
Description:

We confirmed circRNA-MYLK was an oncogene in PCa and revealed a novel mechanism underlying circRNA-MYLK in PC progression.
Other information
Title:

Circular RNA Myosin Light Chain Kinase (MYLK) Promotes Prostate Cancer Progression through Modulating Mir-29a Expression.

Journal: Med Sci Monit
Published: 2018/5/26
PubMed ID: 29798970