circRNA basic information
circBase ID: -
Name: hsa_circ_MYO9B
Synonym: -
Host Gene: hsa-miR-4316
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: breast cancer cell lines (BT474, MCF-7, MDA-MB-231, T47D, MDA-MB-453), normal breast epithelial cell line (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXP4
Associated microRNA: hsa-miR-4316
Biological function: facilitates breast cancer cell proliferation and invasiveness
Molecular mechanism: upregulating FOXP4 expression by sponging hsa-miR-4316
Survival: -
Supported No.:
 1
Description:

In conclusion, our findings demonstrated a key role of circMYO9B/miR-4316/FOXP4 axis in regulating BC progression.
Other information
Title:

Circular RNA circMYO9B facilitates breast cancer cell proliferation and invasiveness via upregulating FOXP4 expression by sponging miR-4316.

Journal: Arch Biochem Biophys
Published: 2018/4/28
PubMed ID: 29702064