circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-135a
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human bladder cancer cell lines (EJ, T24)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-135a
Biological function: inhibited the proliferation, invasion and migration of bladder cancer cells
Molecular mechanism: directly bound to hsa-miR-135a and inhibited its activity in bladder cancer
Survival: -
Supported No.:
 2
Description:

Cdr1as is down-regulated and sponges multiple miRNAs in bladder cancer. It exerts anti-oncogenic functions by sponging microRNA-135a.
Other information
Title:

CircRNA-Cdr1as Exerts Anti-Oncogenic Functions in Bladder Cancer by Sponging MicroRNA-135a.

Journal: Cell Physiol Biochem
Published: 2018/4/26
PubMed ID: 29694981