circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-876-5p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: esophageal cancer cell lines (Eca109, TE1, TE13, KYSE30)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-876-5p
Biological function: increased the proliferation, migration and invasion of ESCC cells
Molecular mechanism: acting as a hsa-miR-876-5p sponge to enhance MAGE-A family expression
Survival: -
Supported No.:
 4
Description:

our study provided novel evidence that ciRS-7 accelerates ESCC progression by acting as a miR-876-5p sponge to enhance MAGE-A family expression.
Other information
Title:

Circular RNA ciRS-7 accelerates ESCC progression through acting as a miR-876-5p sponge to enhance MAGE-A family expression.

Journal: Cancer Lett
Published: 2018/4/11
PubMed ID: 29635069